KIAA1328

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA1328 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1328-associated genes across cancer lineages are eEF2, PCNA, and ASNS. Each is linked with KIAA1328 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA1328-to-partner and partner-to-KIAA1328 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by KIAA1328-low versus KIAA1328-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1328→partner) and Y-score (partner→KIAA1328) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECeEF2 →+0.391+2.000.006.03032
UCECPCNA →+0.351+3.087<.001<.00132
UCECASNS →+0.531+1.906<.001.01632
UCECCaspase-7-cleavedD198 →+0.578+2.604.015.00532
UCECFoxM1 →+0.224+1.906.031.01631
UCECACC1 →+0.315+3.183.031.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

eEF2 by KIAA1328 expression — UCEC

Box plot of eEF2 in KIAA1328-low vs KIAA1328-high samples in UCEC.

Explore this box plot interactively →

Exploration