KIAA1328

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KIAA1328 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA1328-associated genes across cancer lineages are MYOT, NTSR2, and ANO5. Each is linked with KIAA1328 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA1328-to-partner and partner-to-KIAA1328 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYOT grouped by KIAA1328-low versus KIAA1328-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1328→partner) and Y-score (partner→KIAA1328) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEMYOT →+0.111+3.453.001.00931
LARGE_INTESTINENTSR2 →+0.074+4.115<.001.00131
LARGE_INTESTINEANO5 →+0.580+3.453.004.00931
LARGE_INTESTINEUTF1 →+0.015+3.632<.001.00331
LARGE_INTESTINEENTHD1 →+0.028+3.554.002.00731
LARGE_INTESTINESERTM1 →+0.015+3.554.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

MYOT by KIAA1328 expression — LARGE_INTESTINE

Box plot of MYOT in KIAA1328-low vs KIAA1328-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration