KIAA1217

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA1217 mutation is significantly associated with the RNA expression of many other genes, with 5,838 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1217-associated genes across cancer lineages are ZNF662, NDUFA6, and MSANTD3. Each is linked with KIAA1217 in more than 5 cancer types. Because this analysis shows association rather than direction, both KIAA1217-to-partner and partner-to-KIAA1217 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF662 grouped by KIAA1217-low versus KIAA1217-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1217→partner) and Y-score (partner→KIAA1217) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADZNF662 →-0.574-3.572.002.00236
UCECNDUFA6 →+0.436+1.765<.001<.00136
SKCMMSANTD3 →+0.332+1.314<.001<.00135
STADC1QBP →+0.744+3.733<.001<.00135
UCECTRAPPC4 →+0.285+2.222<.001<.00135
UCECTXN2 →+0.262+1.521<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,838 associations by consensus.

ZNF662 by KIAA1217 expression — STAD

Box plot of ZNF662 in KIAA1217-low vs KIAA1217-high samples in STAD.

Explore this box plot interactively →

Exploration