KIAA1217

Across TCGA cell cohorts, KIAA1217 mutation is significantly associated with the RNA expression of many other genes, with 2,492 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA1217-associated genes across cancer lineages are CENPM, TAB1, and NUP98. Each is linked with KIAA1217 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIAA1217-to-partner and partner-to-KIAA1217 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPM grouped by KIAA1217-low versus KIAA1217-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1217→partner) and Y-score (partner→KIAA1217) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CENPM →	+0.903	+2.364	<.001	<.001	3	3
LARGE_INTESTINE	TAB1 →	+0.507	+2.652	.003	.001	3	3
LARGE_INTESTINE	NUP98 →	+0.413	+3.169	.008	.006	3	3
LARGE_INTESTINE	BCL7A →	+0.950	+2.451	<.001	<.001	3	3
LARGE_INTESTINE	DR1 →	+0.586	+1.850	.004	.006	3	3
LARGE_INTESTINE	CASP8AP2 →	+0.622	+2.649	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,492 associations by consensus.

CENPM by KIAA1217 expression — LARGE_INTESTINE

Explore this box plot interactively →