KIAA1143

Across TCGA pan-cancer cohorts, KIAA1143 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KIAA1143 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher KIAA1143 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated KIAA1143 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

CCRCC, LSCC, and PDAC are the cancer types where KIAA1143 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	III,IV	0.903	0.560	.001	25	view →
LSCC	OS	Median	All	0.915	0.742	.005	15	view →
PDAC	DFS	Median	All	0.374	0.212	.007	5	view →
LUAD	OS	Median	II,III,IV	0.770	0.504	.021	5	view →
UCEC	OS	Quartile	II,III,IV	0.525	1.000	.043	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KIAA1143–CCRCC (OS)

Open the CCRCC breakdown →