KIAA1143

Across TCGA patient cohorts, KIAA1143 protein abundance is significantly associated with the RNA expression of many other genes, with 14,912 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KIAA1143-associated genes across cancer lineages are TOP2B, CRBN, and LARS2. Each is linked with KIAA1143 in more than 8 cancer types. Because this analysis shows association rather than direction, both KIAA1143-to-partner and partner-to-KIAA1143 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIAA1143 versus TOP2B in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1143→partner) and Y-score (partner→KIAA1143) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TOP2B →	+0.599	+0.450	<.001	.001	3	9
BRCA	CRBN →	+0.602	+0.364	<.001	<.001	3	8
HNSC	LARS2 →	+0.612	+0.249	.001	.007	3	7
UCEC	WDR48 →	+0.481	+0.245	<.001	<.001	3	7
UCEC	DCAF1 →	+0.759	+0.379	<.001	<.001	3	7
BRCA	SHPRH →	+0.577	+0.331	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,912 associations by consensus.

KIAA1143 vs TOP2B — OV

Explore this scatter interactively →