KIAA1143

Across TCGA patient cohorts, KIAA1143 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1143-associated genes across cancer lineages are F8A2, IGLL4P, and MIR5696. Each is linked with KIAA1143 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA1143-to-partner and partner-to-KIAA1143 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, F8A2 grouped by KIAA1143-low versus KIAA1143-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1143→partner) and Y-score (partner→KIAA1143) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	F8A2 →	+0.054	+4.694	<.001	.007	3	1
UCEC	IGLL4P →	+1.388	+4.256	<.001	.008	3	1
UCEC	MIR5696 →	+0.511	+5.123	<.001	.004	3	1
UCEC	MIR3146 →	+0.739	+4.499	.001	.005	3	1
UCEC	WDR7-OT1 →	+0.189	+4.349	<.001	.007	3	1
SKCM	RNF138P2 →	+0.069	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

F8A2 by KIAA1143 expression — UCEC

Explore this box plot interactively →