KIAA1143

Across TCGA cell cohorts, KIAA1143 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,363 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIAA1143-associated GO terms across cancer lineages are Mitotic spindle assembly, Spindle assembly, and Positive regulation of spindle checkpoint. Each is linked with KIAA1143 in more than 15 cancer types. Because this analysis shows association rather than direction, both KIAA1143-to-partner and partner-to-KIAA1143 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle assembly grouped by KIAA1143-low versus KIAA1143-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1143→partner) and Y-score (partner→KIAA1143) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Mitotic spindle assembly →	+0.080	+0.727	.001	<.001	3	16
LIVER	Spindle assembly →	+0.090	+1.067	.003	.004	3	15
OESOPHAGUS	Positive regulation of spindle checkpoint →	+0.153	+0.897	.002	.001	3	15
OESOPHAGUS	Positive regulation of mitotic cell cycle spindle assembly checkpoint →	+0.153	+0.897	.002	.001	3	15
OESOPHAGUS	Protein localization to condensed chromosome →	+0.183	+0.943	.001	<.001	3	14
SOFT_TISSUE	Regulation of chromosome segregation →	+0.110	+0.541	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,363 associations by consensus.

Mitotic spindle assembly by KIAA1143 expression — BLOOD_Myeloma

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