KIAA0930

Across TCGA pan-cancer cohorts, KIAA0930 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated KIAA0930 data layer compared with 25 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher KIAA0930 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated KIAA0930 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

LSCC, PDAC, and HNSC are the cancer types where KIAA0930 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	All	0.506	0.942	.009	10	view →
PDAC	OS	Quartile	All	0.952	0.772	.011	9	view →
HNSC	DFS	Tertile	All	0.982	0.888	.019	7	view →
CCRCC	OS	Median	All	0.745	0.921	.009	6	view →
LUAD	OS	Median	All	0.774	0.967	.021	6	view →
GBM	OS	Tertile	All	0.457	0.659	.034	4	view →
UCEC	OS	Quartile	All	1.000	0.820	.029	4	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

KIAA0930–LSCC (DFS)

Open the LSCC breakdown →