KIAA0895L

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, KIAA0895L RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of KIAA0895L’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where KIAA0895L RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KIAA0895L is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, COAD, and HNSC are the cancer types where KIAA0895L tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIAA0895L RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCFemaleAll+1.073<.00111view →
COADAllIV+1.441<.00110view →
HNSCMaleAll+0.526<.00110view →
LIHCFemaleII,III,IV+1.175<.0019view →
BLCAAllAll+0.760.0116view →
STADMaleII,III,IV+0.739.0086view →
KICHAllAll−0.571<.0016view →
CHOLMaleAll+2.266<.0013view →
READAllAll+0.822.0062view →
UCECAllAll+0.523.0382view →
LUADFemaleAll+0.449.0062view →
PRADAllAll+0.276.0192view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

Exploration