KIAA0895

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA0895 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0895-associated genes across cancer lineages are RBM15, Gab2, and mTOR. Each is linked with KIAA0895 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0895-to-partner and partner-to-KIAA0895 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBM15 grouped by KIAA0895-low versus KIAA0895-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0895→partner) and Y-score (partner→KIAA0895) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRBM15 →+0.437+3.000.049.03631
UCECGab2 →+0.448+2.321.012.03531
UCECmTOR →-0.287-2.321<.001.03531
UCECNotch1 →+0.160+2.321.023.03531
UCECP-Cadherin →-0.145-2.990.045.03631
UCECVHL →-1.063-3.459.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

RBM15 by KIAA0895 expression — SKCM

Box plot of RBM15 in KIAA0895-low vs KIAA0895-high samples in SKCM.

Explore this box plot interactively →

Exploration