Across TCGA patient cohorts, KIAA0825 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA0825-associated genes across cancer lineages are 4E-BP1, 14-3-3_beta, and EGFR_pY1068. Each is linked with KIAA0825 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIAA0825-to-partner and partner-to-KIAA0825 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0825→partner) and Y-score (partner→KIAA0825) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.230	+2.115	.006	.016	3	3
COAD	14-3-3_beta →	-0.176	-2.196	.024	.010	3	2
COAD	EGFR_pY1068 →	-0.388	-2.213	.001	.010	3	2
UCEC	PDCD4 →	-0.557	-1.893	<.001	<.001	3	2
COAD	Shc_pY317 →	-0.178	-2.983	.005	.034	3	2
COAD	Caspase-7-cleavedD198 →	+0.918	+1.708	.002	.026	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

Exploration

KIAA0825 survival (RNA) · tumor vs normal (RNA) · all KIAA0825 data types