KIAA0586

Across TCGA patient cohorts, KIAA0586 protein abundance is significantly associated with the RNA expression of many other genes, with 2,399 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KIAA0586-associated genes across cancer lineages are AQP9, PDLIM2, and FAM102A. Each is linked with KIAA0586 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0586-to-partner and partner-to-KIAA0586 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIAA0586 versus AQP9 in HNSC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0586→partner) and Y-score (partner→KIAA0586) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	AQP9 →	+1.011	+0.820	.002	<.001	3	2
HNSC	PDLIM2 →	-0.479	-0.980	.003	<.001	3	2
HNSC	FAM102A →	-0.902	-0.932	.006	.001	3	2
LUAD	C1orf116 →	-1.671	-0.442	<.001	<.001	3	2
UCEC	LINC02656 →	+0.922	+1.049	.002	.002	3	2
LUAD	ATP13A4-AS1 →	-1.282	-0.331	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,399 associations by consensus.

KIAA0586 vs AQP9 — HNSC

Explore this scatter interactively →