KIAA0586

Across TCGA cell cohorts, KIAA0586 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,779 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIAA0586-associated GO terms across cancer lineages are Protein localization to condensed chromosome, DNA replication, and Nuclear division. Each is linked with KIAA0586 in more than 17 cancer types. Because this analysis shows association rather than direction, both KIAA0586-to-partner and partner-to-KIAA0586 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to condensed chromosome grouped by KIAA0586-low versus KIAA0586-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0586→partner) and Y-score (partner→KIAA0586) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Protein localization to condensed chromosome →	+0.166	+1.198	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.109	+1.017	<.001	<.001	3	18
OESOPHAGUS	Nuclear division →	+0.105	+1.036	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle →	+0.087	+1.174	<.001	<.001	3	17
OESOPHAGUS	Regulation of chromosome condensation →	+0.202	+0.905	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.120	+1.005	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,779 associations by consensus.

Protein localization to condensed chromosome by KIAA0586 expression — KIDNEY

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