KIAA0319

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA0319 protein abundance is significantly associated with the RNA expression of many other genes, with 1,496 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KIAA0319-associated genes across cancer lineages are CYTH4, TTC28, and THOC5. Each is linked with KIAA0319 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA0319-to-partner and partner-to-KIAA0319 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIAA0319 versus CYTH4 in GBM, with a Pearson correlation of -0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0319→partner) and Y-score (partner→KIAA0319) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCYTH4 →-1.904-0.508.002.00431
GBMTTC28 →+0.596+0.508.004.00431
GBMTHOC5 →+0.532+0.508<.001.00431
GBMMYH9 →-1.237-0.508.002.00431
GBMEFS →+1.212+0.508.003.00431
GBMGINS1 →+1.186+0.508<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,496 associations by consensus.

KIAA0319 vs CYTH4 — GBM

Per-sample scatter of KIAA0319 vs CYTH4 in GBM (Pearson r = -0.79).

Explore this scatter interactively →

Exploration