KIAA0100

Across TCGA pan-cancer cohorts, KIAA0100 Mutation is linked to patient survival in 10 of 34 cancer types, making it a survival-associated KIAA0100 data layer compared with 27 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher KIAA0100 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KIAA0100 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

THYM, OV, and STAD are the cancer types where KIAA0100 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
OV	OS	Median	II,III,IV	0.301	0.693	.003	42	view →
STAD	OS	Median	III,IV	0.147	0.648	<.001	23	view →
HNSC	OS	Median	IV	0.140	0.736	<.001	12	view →
LIHC	DFS	Median	All	0.165	0.451	.005	12	view →
UCEC	DFS	Median	All	0.926	0.607	.003	10	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
GBM	DFS	Median	All	0.064	0.242	.032	3	view →
LUAD	DFS	Median	All	0.121	0.353	.014	2	view →
SKCM	DFS	Median	III,IV	0.816	0.575	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

KIAA0100–THYM (OS)

Open the THYM breakdown →