KIAA0100

Across TCGA pan-cancer cohorts, KIAA0100 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KIAA0100 data layer compared with 27 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher KIAA0100 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KIAA0100 expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

UCEC, CCRCC, and HNSC are the cancer types where KIAA0100 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	III,IV	1.000	0.247	.008	24	view →
CCRCC	DFS	Median	III,IV	1.000	0.809	.012	12	view →
HNSC	DFS	Median	All	0.698	1.000	.020	8	view →
PDAC	DFS	Median	III,IV	0.522	0.224	.033	2	view →
GBM	OS	Median	All	0.653	0.872	.038	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KIAA0100–UCEC (DFS)

Open the UCEC breakdown →