KIAA0100

Across TCGA pan-cancer cohorts, KIAA0100 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of KIAA0100’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where KIAA0100 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types KIAA0100 is over-expressed in tumor, although a few such as LSCC and CCRCC show the opposite, repressed pattern.

LSCC, CCRCC, and OV are the cancer types where KIAA0100 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIAA0100 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LSCC	Male	II,III,IV	−0.170	<.001	8	view →
CCRCC	All	All	−0.144	<.001	7	view →
OV	All	All	−0.524	.011	2	view →
PDAC	All	All	−0.171	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

KIAA0100–LSCC

Open the LSCC breakdown →