KIAA0100

Across TCGA cell cohorts, KIAA0100 mutation is significantly associated with the RNA expression of many other genes, with 1,102 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA0100-associated genes across cancer lineages are C20orf173, ANKRD30BL, and SPP2. Each is linked with KIAA0100 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIAA0100-to-partner and partner-to-KIAA0100 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C20orf173 grouped by KIAA0100-low versus KIAA0100-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA0100→partner) and Y-score (partner→KIAA0100) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	C20orf173 →	+0.132	+3.080	.001	.004	3	2
BREAST	ANKRD30BL →	+0.023	+3.502	<.001	.001	3	2
BREAST	SPP2 →	+0.067	+2.830	<.001	.008	3	2
LARGE_INTESTINE	FBXW10 →	+0.184	+2.906	<.001	.001	3	2
BLOOD_Leukemia	OR9A2 →	+0.030	+3.718	<.001	<.001	3	2
BLOOD_Leukemia	VWC2 →	+0.301	+2.966	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,102 associations by consensus.

C20orf173 by KIAA0100 expression — BREAST

Explore this box plot interactively →