KHSRPP1

Across TCGA patient cohorts, KHSRPP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,028 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KHSRPP1-associated GO terms across cancer lineages are Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Microtubule organizing center localization, and Positive regulation of nucleocytoplasmic transport. Each is linked with KHSRPP1 in more than 22 cancer types. Because this analysis shows association rather than direction, both KHSRPP1-to-partner and partner-to-KHSRPP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by KHSRPP1-low versus KHSRPP1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KHSRPP1→partner) and Y-score (partner→KHSRPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.097	+0.191	.001	.002	2	23
DLBC	Microtubule organizing center localization →	+0.087	+0.195	.003	<.001	2	22
SARC	Positive regulation of nucleocytoplasmic transport →	+0.043	+0.272	<.001	<.001	3	21
STAD	Negative regulation of DNA metabolic process →	+0.047	+0.340	<.001	<.001	3	21
DLBC	Protein depolymerization →	+0.061	+0.208	.003	<.001	3	21
DLBC	Response to cell cycle checkpoint signaling →	+0.127	+0.239	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,028 associations by consensus.

Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by KHSRPP1 expression — DLBC

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