KHNYN

Across TCGA cell cohorts, KHNYN mutation is significantly associated with the mutation status of many other genes, with 2,659 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KHNYN-associated genes across cancer lineages are HPS1, MAPK10, and NCAPG. Each is linked with KHNYN in more than 2 cancer types. Because this analysis shows association rather than direction, both KHNYN-to-partner and partner-to-KHNYN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HPS1 grouped by KHNYN-low versus KHNYN-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHNYN→partner) and Y-score (partner→KHNYN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	HPS1 →	+4.014	+4.969	.008	.008	1	3
BLOOD_Lymphoma	MAPK10 →	+5.014	+5.584	.003	.003	1	3
BLOOD_Lymphoma	NCAPG →	+4.429	+5.247	.005	.005	1	3
OVARY	NOM1 →	+4.977	+4.415	.007	.007	1	3
BLOOD_Lymphoma	CCDC173 →	+5.014	+5.584	.003	.003	1	3
BLOOD_Lymphoma	OR7G1 →	+6.014	+6.014	.001	.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,659 associations by consensus.

HPS1 by KHNYN expression — BLOOD_Lymphoma

Explore this box plot interactively →