KHDRBS2

Across TCGA cell cohorts, KHDRBS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 736 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KHDRBS2-associated GO terms across cancer lineages are Protein-RNA complex assembly, Thiamine-containing compound metabolic process, and Positive regulation of vascular associated smooth muscle cell differentiation. Each is linked with KHDRBS2 in more than 3 cancer types. Because this analysis shows association rather than direction, both KHDRBS2-to-partner and partner-to-KHDRBS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-RNA complex assembly grouped by KHDRBS2-low versus KHDRBS2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDRBS2→partner) and Y-score (partner→KHDRBS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein-RNA complex assembly →	+0.043	+0.920	.003	.004	3	4
BLOOD_Myeloma	Thiamine-containing compound metabolic process →	+0.081	+0.859	.004	.004	3	3
LUNG_NSCLC_LUAD	Positive regulation of vascular associated smooth muscle cell differentiation →	-0.132	-0.385	.001	.008	3	3
LUNG_NSCLC_LUAD	Proteoglycan biosynthetic process →	-0.059	-0.509	<.001	.003	3	3
LUNG_NSCLC_LUAD	Extracellular matrix organization →	-0.057	-0.282	<.001	.005	3	3
LUNG_NSCLC_LUAD	Extracellular structure organization →	-0.057	-0.281	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 736 associations by consensus.

Protein-RNA complex assembly by KHDRBS2 expression — LUNG_SCLC

Explore this box plot interactively →