KHDRBS2-OT1

Across TCGA pan-cancer cohorts, KHDRBS2-OT1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated KHDRBS2-OT1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher KHDRBS2-OT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KHDRBS2-OT1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LUAD show a favorable association.

COAD, PAAD, and LUAD are the cancer types where KHDRBS2-OT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	II,III,IV	0.610	0.863	<.001	93	view →
PAAD	OS	Tertile	All	0.679	0.411	<.001	84	view →
LUAD	OS	Tertile	All	0.759	0.582	<.001	63	view →
ESCA	DFS	Tertile	III,IV	0.622	0.245	.001	54	view →
LGG	OS	Median	All	0.562	0.351	<.001	50	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	37	view →
DLBC	OS	Quartile	IV	0.338	1.000	.010	24	view →
ACC	OS	Tertile	All	0.347	0.785	.017	21	view →
TGCT	OS	Tertile	II,III,IV	0.752	1.000	.019	20	view →
MESO	DFS	Tertile	III,IV	0.541	0.291	.001	19	view →
LUSC	OS	Tertile	IV	0.001	0.651	.025	18	view →
LAML	DFS	Tertile	All	0.213	0.494	.004	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

KHDRBS2-OT1–COAD (OS)

Open the COAD breakdown →