KHDRBS1

Across TCGA pan-cancer cohorts, KHDRBS1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated KHDRBS1 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher KHDRBS1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated KHDRBS1 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

HNSC, COAD, and LUAD are the cancer types where KHDRBS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	II,III,IV	0.776	0.925	.001	87	view →
COAD	DFS	Median	II,III,IV	1.000	0.885	.026	24	view →
LUAD	OS	Median	II,III,IV	0.770	0.507	.025	17	view →
GBM	DFS	Tertile	All	0.424	0.257	.009	16	view →
CCRCC	OS	Tertile	All	0.902	1.000	.017	5	view →
PDAC	DFS	Median	II,III,IV	0.294	0.522	.004	4	view →
LSCC	DFS	Median	III,IV	0.882	1.000	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

KHDRBS1–HNSC (OS)

Open the HNSC breakdown →