KHDRBS1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KHDRBS1 mutation is significantly associated with the RNA expression of many other genes, with 1,323 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KHDRBS1-associated genes across cancer lineages are RNU6-1256P, IMMP1L, and SAA4. Each is linked with KHDRBS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KHDRBS1-to-partner and partner-to-KHDRBS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1256P grouped by KHDRBS1-low versus KHDRBS1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDRBS1→partner) and Y-score (partner→KHDRBS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU6-1256P →+0.406+4.537<.001.00632
UCECIMMP1L →+0.388+2.617.007.00531
UCECSAA4 →-0.830-4.169.001<.00131
UCECPAMR1 →-1.034-3.459.002.00531
UCECEIF3M →+0.457+1.939.006.00931
UCECDRD2 →-0.458-2.393.008.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,323 associations by consensus.

RNU6-1256P by KHDRBS1 expression — COAD

Box plot of RNU6-1256P in KHDRBS1-low vs KHDRBS1-high samples in COAD.

Explore this box plot interactively →

Exploration