KHDRBS1

Across TCGA patient cohorts, KHDRBS1 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KHDRBS1-associated genes across cancer lineages are GAPDH, Rab25, and A-Raf_pS299. Each is linked with KHDRBS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KHDRBS1-to-partner and partner-to-KHDRBS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by KHDRBS1-low versus KHDRBS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDRBS1→partner) and Y-score (partner→KHDRBS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.532	+2.115	.023	.019	3	2
UCEC	Rab25 →	-0.407	-2.459	.004	.019	3	2
UCEC	A-Raf_pS299 →	-0.111	-3.321	.033	.010	3	1
UCEC	Ku80 →	+0.221	+2.128	.032	.010	3	1
UCEC	MEK1 →	+0.385	+2.459	.016	.019	3	1
UCEC	Myosin-IIa_pS1943 →	+0.189	+2.128	.036	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

GAPDH by KHDRBS1 expression — UCEC

Explore this box plot interactively →