KHDRBS1

Across TCGA cell cohorts, KHDRBS1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KHDRBS1-associated genes across cancer lineages are LRIT1, MYL3, and KRTAP5-6. Each is linked with KHDRBS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KHDRBS1-to-partner and partner-to-KHDRBS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRIT1 grouped by KHDRBS1-low versus KHDRBS1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDRBS1→partner) and Y-score (partner→KHDRBS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	LRIT1 →	+0.016	+5.209	<.001	.005	3	1
BLOOD_Leukemia	MYL3 →	+0.116	+3.551	<.001	.009	3	1
BLOOD_Leukemia	KRTAP5-6 →	+0.246	+3.874	<.001	.005	3	1
BLOOD_Leukemia	MAGEL2 →	+0.337	+4.133	.002	.003	3	1
SKIN	OR5B3 →	+0.059	+5.415	<.001	.004	3	1
SKIN	OR10G4 →	+0.006	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

LRIT1 by KHDRBS1 expression — BLOOD_Lymphoma

Explore this box plot interactively →