KHDC4

Across TCGA patient cohorts, KHDC4 protein abundance is significantly associated with the RNA expression of many other genes, with 17,466 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KHDC4-associated genes across cancer lineages are ZNF740, CCDC150, and IMPDH1P8. Each is linked with KHDC4 in more than 5 cancer types. Because this analysis shows association rather than direction, both KHDC4-to-partner and partner-to-KHDC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KHDC4 versus ZNF740 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDC4→partner) and Y-score (partner→KHDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF740 →	+0.630	+0.205	<.001	.001	3	6
BRCA	CCDC150 →	+0.782	+0.186	<.001	.002	3	6
UCEC	IMPDH1P8 →	+1.129	+0.268	<.001	<.001	3	6
HNSC	C1orf112 →	+0.599	+0.205	<.001	<.001	3	6
LSCC	MSH2 →	+0.707	+0.218	<.001	<.001	3	6
OV	LINC01311 →	+0.619	+0.495	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,466 associations by consensus.

KHDC4 vs ZNF740 — UCEC

Explore this scatter interactively →