KHDC4

Across TCGA cell cohorts, KHDC4 RNA expression is significantly associated with the RNA expression of many other genes, with 11,158 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KHDC4-associated genes across cancer lineages are CLK2, GON4L, and DCAF8. Each is linked with KHDC4 in more than 19 cancer types. Because this analysis shows association rather than direction, both KHDC4-to-partner and partner-to-KHDC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KHDC4 versus CLK2 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.89.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDC4→partner) and Y-score (partner→KHDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	CLK2 →	+1.302	+1.125	<.001	<.001	3	20
BONE	GON4L →	+1.087	+1.279	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	DCAF8 →	+1.102	+1.184	<.001	<.001	3	19
BREAST	DENND4B →	+1.338	+1.384	<.001	<.001	3	19
BLOOD_Myeloma	ASH1L →	+1.037	+0.752	<.001	<.001	3	19
SOFT_TISSUE	CREBZF →	+1.358	+1.048	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,158 associations by consensus.

KHDC4 vs CLK2 — UPPER_AERODIGESTIVE_TRACT

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