Across TCGA pan-cancer cohorts, KHDC1P1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of KHDC1P1’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where KHDC1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KHDC1P1 is over-expressed in tumor.
LUSC are the cancer types where KHDC1P1 tumor–normal differential expression is most reproducible.