KHDC1L

Across TCGA pan-cancer cohorts, KHDC1L Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated KHDC1L data layer compared with 22 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher KHDC1L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KHDC1L expression acts as an unfavorable survival marker.

ACC and LIHC are the cancer types where KHDC1L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.188	0.820	<.001	12	view →
LIHC	OS	Median	All	0.255	0.773	.012	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

KHDC1L–ACC (OS)

Open the ACC breakdown →