KHDC1L

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KHDC1L protein abundance is significantly associated with the RNA expression of many other genes, with 676 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible KHDC1L-associated genes across cancer lineages are BCL2L10, TFAP2E, and PLBD1. Each is linked with KHDC1L in more than 1 cancer types. Because this analysis shows association rather than direction, both KHDC1L-to-partner and partner-to-KHDC1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KHDC1L versus BCL2L10 in HNSC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDC1L→partner) and Y-score (partner→KHDC1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCBCL2L10 →+1.358+2.183<.001<.00132
LSCCTFAP2E →+0.646+1.878.004.00132
HNSCPLBD1 →+0.981+2.389<.001<.00132
LSCCS100P →+1.873+1.732.005.00332
HNSCHES5 →+0.847+1.766.001<.00132
LUADPOLK →-1.186-3.833.003<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 676 associations by consensus.

KHDC1L vs BCL2L10 — HNSC

Per-sample scatter of KHDC1L vs BCL2L10 in HNSC (Pearson r = 0.43).

Explore this scatter interactively →

Exploration