KHDC1L

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KHDC1L mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KHDC1L-associated genes across cancer lineages are Adipocytes, Neurons, and Sebocytes. Each is linked with KHDC1L in more than 1 cancer types. Because this analysis shows association rather than direction, both KHDC1L-to-partner and partner-to-KHDC1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by KHDC1L-low versus KHDC1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDC1L→partner) and Y-score (partner→KHDC1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAdipocytes →+0.020+2.507.049.02231
UCECNeurons →-0.022-2.978.038.03731
UCECSebocytes →-0.028-2.978.049.03731
UCECiDC →-0.195-3.000.043.03711
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Adipocytes by KHDC1L expression — UCEC

Box plot of Adipocytes in KHDC1L-low vs KHDC1L-high samples in UCEC.

Explore this box plot interactively →

Exploration