KHDC1L

Across TCGA cell cohorts, KHDC1L RNA expression is significantly associated with the go_rna of many other GO terms, with 2,072 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KHDC1L-associated GO terms across cancer lineages are Post-transcriptional gene silencing, Negative regulation of response to biotic stimulus, and Regulation of post-translational protein modification. Each is linked with KHDC1L in more than 6 cancer types. Because this analysis shows association rather than direction, both KHDC1L-to-partner and partner-to-KHDC1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-transcriptional gene silencing grouped by KHDC1L-low versus KHDC1L-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDC1L→partner) and Y-score (partner→KHDC1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Post-transcriptional gene silencing →	+0.081	+0.337	<.001	.003	3	7
SOFT_TISSUE	Negative regulation of response to biotic stimulus →	+0.068	+0.533	<.001	.001	3	7
STOMACH	Regulation of post-translational protein modification →	+0.056	+0.861	<.001	.003	3	7
STOMACH	Positive regulation of ATP biosynthetic process →	+0.164	+1.444	<.001	.002	3	7
STOMACH	Regulatory ncRNA-mediated gene silencing →	+0.087	+1.298	.002	.006	3	7
STOMACH	Negative regulation of catalytic activity →	+0.043	+0.783	<.001	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,072 associations by consensus.

Post-transcriptional gene silencing by KHDC1L expression — PANCREAS

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