KHDC1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KHDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 628 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KHDC1-associated genes across cancer lineages are MIR2909, CYTH4, and MCM5. Each is linked with KHDC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KHDC1-to-partner and partner-to-KHDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KHDC1 versus MIR2909 in UCEC, with a Pearson correlation of -0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDC1→partner) and Y-score (partner→KHDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR2909 →-1.206-0.877.008.00632
PDACCYTH4 →+0.897+0.907.001<.00131
PDACMCM5 →+0.580+0.811.003<.00131
PDACFOXRED2 →+0.511+0.898<.001<.00131
PDACIL2RB →+0.860+0.706<.001.00431
PDACCORO1A →+1.335+1.109.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 628 associations by consensus.

KHDC1 vs MIR2909 — UCEC

Per-sample scatter of KHDC1 vs MIR2909 in UCEC (Pearson r = -0.59).

Explore this scatter interactively →

Exploration