KHDC1

Across TCGA cell cohorts, KHDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,590 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KHDC1-associated GO terms across cancer lineages are Regulation of mRNA processing, RNA localization, and Regulation of chromosome segregation. Each is linked with KHDC1 in more than 13 cancer types. Because this analysis shows association rather than direction, both KHDC1-to-partner and partner-to-KHDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA processing grouped by KHDC1-low versus KHDC1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KHDC1→partner) and Y-score (partner→KHDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of mRNA processing →	+0.075	+0.786	<.001	.004	3	14
PANCREAS	RNA localization →	+0.088	+1.140	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of chromosome segregation →	+0.126	+1.626	<.001	<.001	3	13
STOMACH	mRNA transport →	+0.110	+1.297	<.001	.005	3	13
BLOOD_Myeloma	RNA splicing, via transesterification reactions →	+0.051	+0.970	.004	<.001	3	13
CNS	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.050	+0.884	.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,590 associations by consensus.

Regulation of mRNA processing by KHDC1 expression — OESOPHAGUS

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