Across TCGA patient cohorts, KEL protein abundance is significantly associated with the RNA expression of many other genes, with 3,610 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KEL-associated genes across cancer lineages are HBA2, HBA1, and ALAS2. Each is linked with KEL in more than 3 cancer types. Because this analysis shows association rather than direction, both KEL-to-partner and partner-to-KEL results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KEL→partner) and Y-score (partner→KEL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HBA2 →	+2.789	+1.019	.004	.001	3	4
GBM	HBA1 →	+1.524	+0.560	<.001	.002	3	4
GBM	ALAS2 →	+0.694	+0.677	.001	<.001	3	3
BRCA	FHL5 →	+1.126	+0.885	.002	.003	3	3
GBM	HEMGN →	+0.315	+0.492	.002	<.001	3	3
LSCC	HBB →	+1.776	+0.629	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,610 associations by consensus.

Exploration

KEL survival (RNA) · tumor vs normal (RNA) · all KEL data types