Across TCGA patient cohorts, KEL mutation is significantly associated with the RNA expression of many other genes, with 3,698 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KEL-associated genes across cancer lineages are STAT6, LRRC37A13P, and MIR920. Each is linked with KEL in more than 3 cancer types. Because this analysis shows association rather than direction, both KEL-to-partner and partner-to-KEL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KEL→partner) and Y-score (partner→KEL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT6 →	-0.328	-1.406	<.001	.009	3	4
GBM	LRRC37A13P →	+0.267	+3.038	<.001	.007	3	3
GBM	MIR920 →	+0.639	+3.115	.001	.006	3	3
UCEC	FGD5 →	-0.509	-1.722	<.001	<.001	3	3
SKCM	PRICKLE2 →	-0.487	-1.289	.001	.003	3	3
UCEC	LSM3 →	+0.522	+1.722	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,698 associations by consensus.

Exploration

KEL survival (RNA) · tumor vs normal (RNA) · all KEL data types