Across TCGA cell cohorts, KEL mutation is significantly associated with the RNA expression of many other genes, with 221 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KEL-associated genes across cancer lineages are ADSL, MEPE, and FAM86B2. Each is linked with KEL in more than 1 cancer types. Because this analysis shows association rather than direction, both KEL-to-partner and partner-to-KEL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KEL→partner) and Y-score (partner→KEL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ADSL →	+0.479	+3.160	.003	.006	3	2
LUNG_NSCLC_LUAD	MEPE →	+0.130	+4.037	<.001	.001	3	2
LARGE_INTESTINE	FAM86B2 →	+0.688	+3.169	.005	.009	3	2
KIDNEY	FFAR2 →	+0.006	+5.000	<.001	.005	3	1
KIDNEY	MROH5 →	+0.006	+5.000	<.001	.005	3	1
LUNG_NSCLC_LUSC	USP17L15 →	+0.006	+4.643	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 221 associations by consensus.

Exploration

KEL survival (RNA) · tumor vs normal (RNA) · all KEL data types