KDSR

Across TCGA pan-cancer cohorts, KDSR mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated KDSR data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher KDSR mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated KDSR expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

CCRCC, LSCC, and UCEC are the cancer types where KDSR mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	II,III,IV	0.454	1.000	.014	8	view →
LSCC	DFS	Quartile	III,IV	0.275	0.941	.009	5	view →
UCEC	DFS	Quartile	All	0.826	1.000	.017	4	view →
PDAC	DFS	Tertile	III,IV	0.537	0.198	.019	3	view →
LUAD	OS	Median	III,IV	0.265	1.000	.034	2	view →
HNSC	OS	Tertile	II,III,IV	1.000	0.947	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

KDSR–CCRCC (OS)

Open the CCRCC breakdown →