KDSR

Across TCGA patient cohorts, KDSR RNA expression is significantly associated with the protein abundance of many other proteins, with 11,777 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KDSR-associated proteins across cancer lineages are SMAD4, TRAPPC8, and VPS4B. Each is linked with KDSR in more than 6 cancer types. Because this analysis shows association rather than direction, both KDSR-to-partner and partner-to-KDSR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDSR versus SMAD4 in PDAC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KDSR→partner) and Y-score (partner→KDSR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SMAD4 →	+0.253	+0.428	.001	<.001	3	7
LUAD	TRAPPC8 →	+0.152	+0.358	<.001	.001	3	5
LSCC	VPS4B →	+0.220	+0.375	<.001	.008	3	5
BRCA	SND1 →	-0.224	-0.503	.005	<.001	3	4
UCEC	TMX3 →	+0.551	+0.405	<.001	<.001	3	4
OV	ECHS1 →	-0.469	-0.590	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,777 associations by consensus.

KDSR vs SMAD4 — PDAC

Explore this scatter interactively →