KDSR

Across TCGA cell cohorts, KDSR RNA expression is significantly associated with the go_rna of many other GO terms, with 4,087 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KDSR-associated GO terms across cancer lineages are ESCRT complex disassembly, ESCRT III complex disassembly, and Ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway. Each is linked with KDSR in more than 11 cancer types. Because this analysis shows association rather than direction, both KDSR-to-partner and partner-to-KDSR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ESCRT complex disassembly grouped by KDSR-low versus KDSR-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDSR→partner) and Y-score (partner→KDSR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	ESCRT complex disassembly →	+0.135	+1.007	<.001	<.001	3	12
SOFT_TISSUE	ESCRT III complex disassembly →	+0.135	+1.007	<.001	<.001	3	12
LARGE_INTESTINE	Ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway →	+0.133	+1.157	<.001	<.001	3	10
BREAST	GCN2-mediated signaling →	+0.140	+0.818	<.001	.003	3	9
LIVER	Dephosphorylation →	+0.068	+1.347	<.001	<.001	3	9
LARGE_INTESTINE	Positive regulation of exosomal secretion →	+0.104	+1.069	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,087 associations by consensus.

ESCRT complex disassembly by KDSR expression — SOFT_TISSUE

Explore this box plot interactively →