KDR

Across TCGA patient cohorts, KDR RNA expression is significantly associated with the protein abundance of many other proteins, with 15,695 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible KDR-associated proteins across cancer lineages are VWA1, FMNL3, and LAMA4. Each is linked with KDR in more than 7 cancer types. Because this analysis shows association rather than direction, both KDR-to-partner and partner-to-KDR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDR versus VWA1 in CCRCC, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KDR→partner) and Y-score (partner→KDR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	VWA1 →	+0.617	+1.362	<.001	<.001	3	8
UCEC	FMNL3 →	+0.417	+0.568	<.001	.009	3	8
GBM	LAMA4 →	+0.654	+0.814	<.001	<.001	3	8
CCRCC	TNS2 →	+0.488	+1.290	<.001	<.001	3	7
CCRCC	PLVAP →	+0.876	+1.146	<.001	<.001	3	7
UCEC	PRKG1 →	+0.744	+0.697	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,695 associations by consensus.

KDR vs VWA1 — CCRCC

Explore this scatter interactively →