KDM7A

Across TCGA pan-cancer cohorts, KDM7A mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated KDM7A data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher KDM7A mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KDM7A expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

LSCC and HNSC are the cancer types where KDM7A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	All	1.000	0.832	.016	4	view →
HNSC	DFS	Quartile	III,IV	0.937	0.527	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

KDM7A–LSCC (DFS)

Open the LSCC breakdown →