KDM7A

Across TCGA patient cohorts, KDM7A protein abundance is significantly associated with the RNA expression of many other genes, with 607 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KDM7A-associated genes across cancer lineages are TMEM220, TBC1D17, and NPTX2. Each is linked with KDM7A in more than 1 cancer types. Because this analysis shows association rather than direction, both KDM7A-to-partner and partner-to-KDM7A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM7A versus TMEM220 in HNSC, with a Pearson correlation of -0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM7A→partner) and Y-score (partner→KDM7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TMEM220 →	-0.840	-0.540	.004	.003	3	2
UCEC	TBC1D17 →	+1.015	+0.690	.002	<.001	3	1
UCEC	NPTX2 →	-0.763	-0.595	.001	<.001	3	1
UCEC	USP46 →	+1.035	+0.587	<.001	.002	3	1
UCEC	CDH6 →	-1.921	-0.595	.001	<.001	3	1
UCEC	CD180 →	-1.103	-0.594	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 607 associations by consensus.

KDM7A vs TMEM220 — HNSC

Explore this scatter interactively →