KDM7A

Across TCGA cell cohorts, KDM7A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,562 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KDM7A-associated GO terms across cancer lineages are Copper ion export, Negative regulation of hematopoietic stem cell differentiation, and Erythrocyte homeostasis. Each is linked with KDM7A in more than 12 cancer types. Because this analysis shows association rather than direction, both KDM7A-to-partner and partner-to-KDM7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion export grouped by KDM7A-low versus KDM7A-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM7A→partner) and Y-score (partner→KDM7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Copper ion export →	-0.180	-0.958	<.001	<.001	3	13
URINARY_TRACT	Negative regulation of hematopoietic stem cell differentiation →	+0.128	+1.067	<.001	<.001	3	10
PANCREAS	Erythrocyte homeostasis →	+0.049	+0.841	.002	<.001	3	10
STOMACH	Regulation of glycogen metabolic process →	+0.081	+1.548	.002	<.001	3	10
BREAST	Blood coagulation, intrinsic pathway →	-0.275	-1.269	.004	.003	3	10
BONE	Pre-mRNA catabolic process →	+0.242	+1.318	.001	.006	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,562 associations by consensus.

Copper ion export by KDM7A expression — BLOOD_Leukemia

Explore this box plot interactively →