KDM6A

Across TCGA patient cohorts, KDM6A RNA expression is significantly associated with the protein abundance of many other proteins, with 9,100 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible KDM6A-associated proteins across cancer lineages are UBA1, PUDP, and RPS4Y1. Each is linked with KDM6A in more than 6 cancer types. Because this analysis shows association rather than direction, both KDM6A-to-partner and partner-to-KDM6A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM6A versus UBA1 in COAD, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM6A→partner) and Y-score (partner→KDM6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	UBA1 →	+0.223	+0.489	<.001	<.001	3	7
LUAD	PUDP →	+0.488	+0.447	<.001	<.001	3	7
COAD	RPS4Y1 →	-1.298	-0.553	<.001	<.001	3	6
PDAC	DDX3X →	+0.256	+0.464	<.001	<.001	3	6
PDAC	DDX3Y →	-2.198	-0.490	<.001	<.001	3	6
PDAC	DDX3Y_S592 →	-2.197	-0.526	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,100 associations by consensus.

KDM6A vs UBA1 — COAD

Explore this scatter interactively →