KDM6A

Across TCGA patient cohorts, KDM6A protein abundance is significantly associated with the RNA expression of many other genes, with 5,436 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible KDM6A-associated genes across cancer lineages are ZNF839P1, CDY4P, and LINC00278. Each is linked with KDM6A in more than 5 cancer types. Because this analysis shows association rather than direction, both KDM6A-to-partner and partner-to-KDM6A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM6A versus ZNF839P1 in GBM, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM6A→partner) and Y-score (partner→KDM6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZNF839P1 →	-1.631	-0.189	<.001	.005	3	6
GBM	CDY4P →	-1.399	-0.228	<.001	.001	3	6
CCRCC	LINC00278 →	-1.769	-0.360	.006	.003	3	6
LUAD	ZFY →	-1.948	-0.213	<.001	<.001	3	6
LUAD	PRKY →	-1.710	-0.210	<.001	<.001	3	5
GBM	KDM5C →	+0.491	+0.310	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,436 associations by consensus.

KDM6A vs ZNF839P1 — GBM

Explore this scatter interactively →