Across TCGA patient cohorts, KDM5C RNA expression is significantly associated with the go_rna of many other GO terms, with 7,153 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible KDM5C-associated GO terms across cancer lineages are Protein demethylation, Positive regulation of stem cell population maintenance, and Obsolete regulation of histone methylation. Each is linked with KDM5C in more than 31 cancer types. Because this analysis shows association rather than direction, both KDM5C-to-partner and partner-to-KDM5C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM5C→partner) and Y-score (partner→KDM5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Protein demethylation →	+0.105	+1.370	<.001	<.001	3	32
DLBC	Positive regulation of stem cell population maintenance →	+0.050	+1.037	.001	<.001	3	31
UCS	Obsolete regulation of histone methylation →	+0.077	+0.970	<.001	<.001	3	31
SCLC	Cytoplasmic microtubule organization →	+0.092	+1.047	.002	<.001	3	31
UCS	Establishment of mitotic sister chromatid cohesion →	+0.106	+1.008	<.001	<.001	3	31
DLBC	Interstrand cross-link repair →	+0.068	+1.292	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,153 associations by consensus.

Exploration

KDM5C survival (RNA) · tumor vs normal (RNA) · all KDM5C data types