KDM5A

Across TCGA patient cohorts, KDM5A protein abundance is significantly associated with the RNA expression of many other genes, with 8,625 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KDM5A-associated genes across cancer lineages are ITFG2, RAD52, and RAD51AP1. Each is linked with KDM5A in more than 5 cancer types. Because this analysis shows association rather than direction, both KDM5A-to-partner and partner-to-KDM5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM5A versus ITFG2 in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM5A→partner) and Y-score (partner→KDM5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ITFG2 →	+0.765	+0.240	.002	.003	3	6
OV	RAD52 →	+0.624	+0.226	.002	.004	3	5
BRCA	RAD51AP1 →	+0.985	+0.195	<.001	.001	3	5
HNSC	CCDC77 →	+0.722	+0.245	<.001	<.001	3	5
LSCC	CPSF6 →	+0.656	+0.199	<.001	<.001	3	4
LSCC	DCP1B →	+0.609	+0.201	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,625 associations by consensus.

KDM5A vs ITFG2 — OV

Explore this scatter interactively →